Posting Description
TECHNICAL ASSOCIATE I, Mechanical Engineering, will sustain day-to-day sterile culture and experimental workflows for human epithelial/stromal organoids. The position provides the dedicated hands-on capacity required to maintain quality control, documentation, and compliance for human-derived sample handling, while enabling consistent sample preparation for downstream profiling and ongoing collaborations. Responsibilities will include: Research Techniques and Protocols (70%) to establish and maintain human epithelial and stromal organoids under sterile, no-antibiotic conditions, assist in stem cell–epithelial co-culture experiments for modeling cell–cell and matrix–cell interactions, conduct growth factor, drug treatment, and CRISPR-based perturbation experiments, prepare and handle growth media, growth factors, and supplements as needed for the experimental protocol, and prepare samples for downstream molecular assays (RNA-seq, proteomics, or spatial-omics); Research and Document Production (10%): to present updates at lab meetings and contribute to manuscripts and proposals; and Data/Analysis (20%): to measure adhesive properties, zeta potential, pH, and cell response to external stresses; collaborate with the engineering team to link these measurements with device-based assays; and record, organize, and manage experiment metadata and results for computational analysis pipelines.