Posting Description

TECHNICAL ASSOCIATE I, YAFFE LAB, Koch Institute for Integrated Cancer Research-Yaffe Lab, to work closely with several lab members and perform independent research using CRISPR-based screens for sensitization of tumor cells to signaling pathway inhibitors and chemotherapeutic drugs, combined with in vivo mouse tumor studies.  Responsibilities include performing a broad range of basic laboratory experiments using standard techniques, including tissue culture techniques, CRISPR screening, maintaining mouse tumor and human PDX models, delivery of novel anti-cancer therapeutics into mice and target tumors, molecular cloning, immunoblotting, flow cytometry, and other biochemical/molecular assays; statistical data analysis; evaluating, designing, and revising research methods/procedures/techniques based on established objectives; and adjusting basic experimental protocols to ensure project completion in a timely fashion.