**At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.** We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: _“What would I do if this patient were my mom?”_ That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. **Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.** **Position Summary** The Data and Software Engineering team at Caris Life Sciences is looking for a Software Engineer with a desire to make a real difference immediately and a drive to continuously learn new technologies in software, data, and biotechnology. This role focuses on services and applications, with opportunities to develop core data science infrastructure. The ideal candidate brings expertise in Python, AWS, Gen AI, and web application development. This role involves evolving codebases, extending production pipelines, and building new infrastructure - all while leveraging cutting-edge cloud technologies, Gen AI solutions, and Big Data environments. **Job Responsibilities** + Execute full software development life cycle (SDLC) + Monitor and maintain our data pipeline and application infrastructures to ensure continuous operation in an AWS environment + Develop and integrate Gen AI solutions to improve workflows and automation + Develop production-grade software systems that incorporate AI/ML, LLMs, and agentic workflows + Develop and enhance full-stack applications using Python, Django/Flask, and React + Collaborate with cross-functional teams, product managers, and business analysts to define requirements, develop specifications, and deliver software solutions + Monitor and enhance our CI/CD capabilities in GitLab + Monitor and optimize application performance, troubleshoot issues, and implement solutions to enhance user experience + Create and maintain technical documentation for software systems and processes + Stay updated on emerging technologies and industry best practices, and contribute to continuous improvement and innovation within the team **Required Qualifications** + Bachelor's degree in Computer Science, Software Engineering, or related field. + 3-5 years of professional software development experience building enterprise-level applications + Strong hands-on Python experience with solid programming fundamentals + Hands-on experience with AWS cloud services and infrastructure + Experience with Gen AI development: LLMs, prompt engineering, and agentic systems + Proficiency in version control, CI/CD pipelines, and DevOps + Strong problem-solving skills and attention to detail, with the ability to analyze complex issues and implement effective solutions + Customer-centric attitude and passion for providing high-quality services **Preferred Qualifications** + Experience with workflow orchestration frameworks such as Metaflow, Nextflow, or Airflow + Experience building cloud-native web applications, particularly with React + Experience with data engineering concepts including SQL, ETL pipelines, and data modeling + Hands-on experience with containerization technologies such as Docker + Experience using CDK to deploy and manage AWS infrastructure **Physical Demands** + Will work at computer most of the time **Training** + All job specific, safety, and compliance training are assigned based on the job functions associated with this employee. **Other** + This position requires periodic travel and some evenings, weekends and/or holidays. **Annual Hiring Range** $100,000 - $120,000 Actual compensation offer to candidate may vary from posted hiring range based upon geographic location, work experience, education, and/or skill level. The pay ratio between base pay and target incentive (if applicable) will be finalized at offer. **Description of Benefits** + Highly competitive and inclusive medical, dental and vision coverage options + Health Savings Account for medical expenses and dependent care expenses + Flexible Spending Account to pay for certain out-of-pocket expenses + Paid time off, including: vacation, sick time and holidays + 401k match and Financial Planning tools + LTD and STD insurance coverages, as well as voluntary benefit options + Employee Assistance Program + Pet Insurance + Legal Assistance + Tuition Assistance **Conditions of Employment:** Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification. This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time. Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability. Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation. Caris is committed to quality and excellence at our state-of-the-art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.