At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** In Roche’s Pharmaceutical Research and Early Development organization (pRED (https://www.roche.com/innovation/structure/pred/) ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. **The Opportunity** As a Project Team Leader (PTL) in Cardiovascular, Metabolism and Immunology (CMI) in pRED, you will act as the project leader for one or more immunology asset teams, assuming full accountability for the development of drug candidates through to pivotal studies. You will lead the team in developing and executing on an asset strategy that delivers on portfolio strategic priorities and maximises value for patients. For the teams you lead, you will: + Embed the principles and ways of working for a high performing asset team + Lead the team to develop and implement an innovative asset strategy with appropriate data driven stage-gates, de-risking approaches and mitigation strategies + Lead co-development projects, balancing the needs of Roche and partners in collaborations + Communicate critical data and project team recommendations and decisions to key governance committees and drive stage-gate milestones and budget requests + Serve as the interface between CMI in pRED and partner functions on project-related issues + Actively engaging with other PTLs and the CMI leadership team to drive portfolio strategy and trade-off decisions **Who you are** You have led matrix research or development project teams in a complex and fast-paced organization. You have clear and effective communication skills, a deep knowledge of strategic drug development and experience in clinical development. You have demonstrated the ability to influence and align with a diversity of stakeholders in a large organisation and have a track record of shaping decisions without formal authority. + You hold a PhD, MD, PharmD, or equivalent experience. + You have at least 8 years in the pharmaceutical industry with broad cross-functional experience. + You have spent at least 5 of these years in pre-clinical and/or clinical development roles, with pre-clinical and/or early clinical development experience preferred. + You have extensive matrix leadership or line leadership experience. + You have experience in defining and communicating project strategy in a variety of contexts. + A background in the CMI Immunology focus areas of respiratory, gastroenterology or nephrology/rheumatology is preferred. Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity! Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process. **Who we are** A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. **Roche is an Equal Opportunity Employer.**