Job Title: Production Technician III — Downstream Purification Job Description The Production Technician III plays a crucial role in executing cGMP manufacturing activities in a regulated biologics environment, with a specialized focus on Downstream Purification. This position operates during the night shift, working 12-hour shifts on a 2-2-3 schedule. The technician will independently perform complex processing tasks, support troubleshooting and deviation resolutions, and serve as a technical resource for newer technicians. Responsibilities + Execute downstream purification operations in accordance with batch records, SOPs, and cGMP requirements. + Operate and monitor chromatography systems using Unicorn software, including method execution, alarms, and system performance. + Perform purification unit operations such as chromatography, buffer preparation, solution transfers, and filtration. + Conduct in-process sampling and analyses (e.g., pH, conductivity, UV) and document results per GDP standards. + Perform equipment setup, changeover, CIP/SIP, and line clearance activities. + Troubleshoot process and equipment issues; support deviation investigations and corrective actions. + Train and mentor Production Technician I and II personnel. + Maintain compliance with safety, environmental, and quality regulations. Essential Skills + Advanced experience in downstream purification, specifically chromatography using Unicorn software. + Strong understanding of cGMP manufacturing and electronic or paper batch record execution. + Ability to work independently on night shift and support continuous operations. Additional Skills & Qualifications + High School Diploma or GED with 2 years of related experience, or Associate’s degree in life science with 0–1 years of related experience, or equivalent military training or experience. + Preferred: BioWork Certificate. + 2+ years of experience in a cGMP manufacturing environment is preferred. Work Environment The role requires working in environments with temperatures ranging from 0°F to 100°F. Technicians may work in small or enclosed spaces, at heights greater than 4 feet, and are required to have the ability to discern audible cues, perform tasks requiring 20/20 corrected vision, and perform repetitive motions. The position involves standing or sitting for prolonged periods and lifting up to 33 lbs. Respiratory protection may be required, and work does not routinely occur outdoors or involve operating powered industrial trucks. Job Type & Location This is a Contract position based out of Morrisville, NC. Pay and Benefits The pay range for this position is $25.00 - $30.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Morrisville,NC. Application Deadline This position is anticipated to close on Feb 4, 2026. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.