**To ensure a rapid processing of your application, please apply only via the “Apply” button. Please include a letter of motivation and a current resume with your application.** **In your cover letter, please highlight your motivation to apply, and how your experience and skillset are connected to this position.** About the job **Our Team:** At Sanofi, we chase the miracles of science to improve people’s lives. In the Global CMC department of R&D we develop industrial-scale production processes to bring our pipeline medicines to the patient. As part of the Microbial Platform in Frankfurt, we are developing cutting edge manufacturing processes for the next generation of microbial-derived biologics. To support our Host Strain Development Team in Frankfurt, we are looking for a highly self-motivated, innovative Laboratory Head with passion for microbial biotechnology and synthetic biology who is eager to bring research into application for the benefit of patients. **Main responsibilities:** + Lead and manage a team of technicians, post-docs/scientists, and students + Lead planning and design of microbial strain engineering, molecular biological experiments, expression tests and process development + Responsible for the generation of high performing microbial strains producing our pipeline molecules - from expression construct design to generation of non-GMP cell banks + Development, evaluation, and implementation of new methods or applications and optimization of existing state-of-the-art process-relevant methods and molecular biological techniques + Data analysis and data interpretation, presentation and reporting of results to international and interdisciplinary audience + Spearhead the implementation of high-throughput methods and AI-supported data analysis + Work independently as a fully integrated member of a cross-functional, interdisciplinary, and international CMC development team and contribute to interdisciplinary CMC project teams + Collaborate with global teams across Research, Production, and Outsourcing + Follow, review, and share the latest project-related innovations and technology breakthroughs in academia and industry + Contribute to collaborations with academic institutions + Ensure compliance with safety and regulatory requirements About you **Experience** : + PhD with experience in molecular biology, microbiology, biochemistry, and microbial expression systems or a closely related field + 3 – 5 years of industry experience in the biopharmaceutical environment + Proven leadership experience (personnel management) + Track record within the field of recombinant protein expression technology, synthetic biology, and strain engineering with strong focus on bacterial expression systems like _E. coli_ and/or yeast, especially _Pichia pastoris_ ( _Komagataella phaffii_ ) **Scientific Skills:** + Expert knowledge in modern molecular biology techniques, microbiology and strong background in _E. coli_ and/or yeast ( _P. pastoris_ ) genetics, physiology and strain engineering + Experience with DNA sequence design, genome databases, cloning software (e. g. SnapGene) and electronic lab notebooks (e. g. Benchling) + Experience with genome engineering techniques of microbial strains + Experience with high-throughput screening methods + Proficiency in automated data analysis and visualization + Understanding of AI-supported processes in biotechnology + Experience with complex laboratory equipment and robotic systems + Experience with NGS techniques and/or NGS data analysis is a plus **Soft Skills** : + Passionate about biotechnology and synthetic biology + Strong communication skills in cross-functional, international settings + Strategic thinking, innovative mindset and entrepreneurial spirit + Excellence in project management + Ability to drive a scientific project from idea to application, "Can Do”-Attitude + Demonstrated ability/willingness to quickly learn and perform in new areas, implement new techniques and instrumentation + Elaborate, structured and accurate way of working + Strong team player with analytical skills and interest to work in a highly interdisciplinary area **Languages** : + Fluent in English, preferably good German skills Why choose us? + Bring the miracles of science to life alongside a supportive, future-focused team. + Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. + Benefit from a well-thought-out benefits package that rewards your contribution and commitment. + We take care of you and your family with a wide range of health and social such as high-quality healthcare, numerous prevention programs and coverage for long-term illness. Our 14-week paid family leave for both parents is outstanding as well as a wide range of childcare benefits. + Start your career at an attractive location in the center of Germany and experience our modern working environment and benefit from hybrid, flexible working time models. **Pursue** **_Progress_** **. Discover** **_Extraordinary_** **.** Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! \#LI-Onsite \#MicrobialStrainEngineering \#MolecularBiology \#Biotechnology \#GenomeEngineering \#Sanofi (https://www.linkedin.com/feed/hashtag/?keywords=sanofi&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7227338801126264833) \#SanofiCareers \#PursueProgress (https://www.linkedin.com/feed/hashtag/?keywords=pursueprogress&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7209134303526436865) \#DiscoverExtraordinary \#WeNeverSettle (https://www.linkedin.com/feed/hashtag/?keywords=weneversettle&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7228792518958551040) \#TeamSanofi \#IgnitingPotential (https://www.linkedin.com/feed/hashtag/?keywords=ignitingpotential&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7224858521010384896) **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)