The Precision Medicine group at Regeneron is responsible for designing, implementing, executing, analyzing and interpreting the overarching clinical biomarker strategies for therapeutic candidates during clinical development. We are seeking to hire a hands-on Precision Medicine Strategy Lead (PMSL) roles at the director level, with backgrounds in one or more therapeutic areas within the group. We are seeking someone to independently oversee the development and execution of biomarker strategies across one (or more) therapeutic areas depending on their areas of expertise, with a preference in obesity / metabolism pharmaceutical development.. The following therapeutic areas are in scope: Neurodegenerative Disorders, Cardiovascular Disease, Muscle and Metabolism Disorders, and/or Rare Genetic Diseases). In this highly matrixed role, they will design, develop, communicate at senior levels and operationally implement clinical biomarker strategies to support key programs in early and late stage drug development. Clinical technologies applied include biomarker assays, pharmacogenetic assessments, as well as other clinical and physiological testing devices.

A typical day may include:

Enhancing our understanding of indications at a cellular and molecular level

Conducting novel biomarker discovery, qualifying new biomarkers/approaches to expedite proof-of-concept for new drug candidates.

Optimizing label claims for later stage candidates, enabling personalized medicine principles to be applied, as appropriate, in full development.

With a focus in therapeutic areas outside of Oncology, broad understanding of disparate biomarker technologies, and deep experience in biomarker assay development and validation in clinical drug development

Responsible for conducting in-depth literature and technology reviews pertinent to assigned clinical development programs within the TFA, identifying and pulling in experts in multiple disease areas, navigating and supporting the logistical and regulatory factors pertaining to clinical technologies.

This role may be for you if have experience with the following:

TA--level lead for implementation of strategic vision for clinical biomarkers in one or more therapeutic areas across multiple programs with multiple studies that will broadly enable advances in target identification, indication selection, early indication of biological activity and patient stratification/selection

Serve as an individual contributor and senior-level representative of Precision Medicine on development teams and deliver biomarker strategies to key programs from initial concept to execution, data delivery and results interpretation

Collaborate with Discovery Research and product development teams to facilitate appropriate incorporation of Precision Medicine and clinical biomarker strategies for molecules in discovery phases (leading to candidate molecule selection)

Represent Regeneron and work with colleagues from allied companies to develop and implement strategies for partnered alliances

Collaborate with clinical operations teams to implement specific biomarker and exploratory sample collection and analyses in all relevant clinical studies in selected programs

Design, oversee and manage internal and external research collaborations in areas of clinical technologies and translational research

 Accountability for ensuring complex clinical assays used in programs in the TFA portfolio of clinical development are fit-for-purpose (whether developed and validated internally or externally)

Collaborate with internal Regeneron laboratories (e.g. Discovery Research, Molecular Profiling, Regeneron Genetics Center, DNA core, BioAnalysis, etc.) to develop plan for validation and application of research assays

Ensure timely delivery of results across selected programs, consistent with program team and senior management expectations in a way that increases the potential impact of Precision Medicine deliverables on Global Development programs

 Contribute to and ensure the quality of Precision Medicine technical reports, study memos and clinical study reports, data reviews and interpretations, scientific publications and recommendations to development teams and management.

To be considered for this role, you must have a PhD and 10+ years of experience driving, managing, executing and delivering results for complex multi-functional projects. You have excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills. Strong track record in mentorship and development of direct reports.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location.  In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.  For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together.  For that reason, many of Regeneron’s roles are required to be performed on-site.  Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.
 

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions.  For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process.  Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)