Job Title: Director of Clinical Operations We are seeking proactive candidates for an upcoming Director of Clinical Operations position. The Director of Clinical Operations will lead the planning, execution, and oversight of clinical programs across our oncology portfolio. This role is central to driving high‑quality, timely, and compliant clinical trial delivery in a fast‑moving biotech environment. You will partner closely with Clinical Development, Regulatory, Biometrics, CMC, and external partners to ensure our studies advance efficiently and with scientific and operational excellence. This is a strategic and hands‑on leadership position suited for someone who thrives in an innovative, mission‑driven organization working to bring transformative cancer therapies to patients. Responsibilities Clinical Strategy & Leadership + Provide strategic operational leadership for all clinical programs, from first‑in‑human through late‑stage oncology trials. + Translate clinical development plans into executable operational strategies, timelines, and budgets. + Serve as a key member of cross‑functional program teams, representing Clinical Operations in strategic decision‑making. Trial Planning & Execution + Oversee end‑to‑end clinical trial operations, including site selection, study start‑up, enrollment strategy, monitoring, data collection, and close‑out. + Ensure trials are conducted in accordance with ICH‑GCP, regulatory requirements, and internal SOPs. + Lead vendor selection, contracting, and ongoing oversight (CROs, labs, imaging vendors, eCOA, etc.). + Anticipate operational risks and proactively implement mitigation strategies. Team Management & Development + Build, mentor, and lead a high‑performing Clinical Operations team, including Clinical Trial Managers, Clinical Research Associates, and contractors. + Foster a culture of accountability, collaboration, and continuous improvement. Cross‑Functional Collaboration + Partner with Clinical Development, Medical Affairs, Regulatory, Biometrics, and CMC to ensure alignment across program objectives. + Work closely with Quality to support audits, inspections, and CAPA implementation. + Collaborate with Finance on forecasting, budgeting, and resource planning. Data & Quality Excellence + Ensure data integrity, patient safety, and operational quality across all studies. + Drive inspection readiness and support regulatory submissions (INDs, CTAs, NDAs/BLAs). + Champion operational best practices and process optimization. Essential Skills Bachelor’s degree in life sciences or related field; advanced degree preferred. 8+ years of clinical operations experience in biotech/pharma, with at least 5 years in oncology. Proven track record leading global clinical trials, including early‑phase oncology studies. Strong understanding of ICH‑GCP, FDA/EMA regulations, and oncology‑specific operational considerations (e.g., biomarker-driven enrollment, imaging endpoints, complex safety profiles). Experience managing CROs and external vendors. Demonstrated leadership ability with experience building and developing teams. Excellent communication, problem‑solving, and organizational skills. Work Environment This position is hybrid. Must be located in San Diego, CA. Job Type & Location This is a Contract position based out of San Diego, CA. Pay and Benefits The pay range for this position is $90.00 - $120.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully remote position. Application Deadline This position is anticipated to close on Feb 24, 2026. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.