At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** We advance science so that we all have more time with the people we love. Doing now what patients need next. A pioneer in the development of blood glucose monitoring and insulin delivery systems, Roche is committed to helping people with diabetes everywhere in the world through a broad portfolio of solutions for both people with diabetes and their professionals. Combining the strengths of our portfolio of Diabetes Care as well as Point of Care products, the organization 'Near Patient Care Operations Mannheim/Indianapolis' aims to achieve best-in-class manufacturing and operational excellence, delivering the highest quality solutions for patients and Health Care Professionals. We are looking for you as an _Application & Integration Architect_ . In this role, you will be a part of Digital Operations, which is a function within Global Engineering to support the production of diagnostic units for our patients. Our global team provides the integration between manufacturing and the enterprise with systems including MES, SAP, lab systems, and cybersecurity; from development to support to lifecycle management. **The Opportunity** + In collaboration with IT and business partners, monitor and improve stakeholder and user experience to maximize utilization of Manufacturing applications and systems. Analyse and interpret data to provide recommendations for process improvements. + Capable of gathering user requirements process steps and translating them to system requirements. + You will assist in delivering internally and externally built systems. + Provides technical support for Manufacturing applications to end users and key business users. (On-call-support, including regular intervals outside of regular working hours). + Work independently to learn and investigate solutions; while also capable of collaborating and learning from other team members. + Work in local and global projects in the area of Manufacturing applications. + Exchange technical information with employees at other locations and form a network. + Travel for this position is expected to be approximately 20%. **Who You Are:** + Bachelor’s Degree in Computer Science, Information Systems, Business Administration or other related field or equivalent work experience + 8+ years related experience **Preferred Experience / Skills** + Define overall MES (Camstar/Opcenter preferred) architecture and roadmap + Translate user (IT, Eng, Mfg, Quality) needs into functional and technical specs. + Design interfaces with ERP (i.e. SAP), Quality systems and shop-floor systems + Lead project teams, mentor staff, and manage technical delivery + Define data models, flows, and integration standards + Ensure solutions meet GMP, FDA, and data integrity requirements. + Oversee system deployment, upgrades, patches, and production support. + Deep Camstar/Opcenter expertise, C#, Java, SQL, integration patterns, scripting. + Strong understanding of production processes, quality, and master data + Project leadership, team motivation, vendor management, excellent communication. **Locations** You are based in Indianapolis. Relocation benefits are not available for this position. The expected salary range for the Senior Manufacturing Engineer position based on the primary location of Indiana is $105,700 - $196,300 Annual. Actual pay will be determined based on experience, qualifications and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance, as well as participation in a long-term incentive program. This position also qualifies for the benefits detailed at the link provided below. **Who we are** A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE\_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .