At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Investigational ADME, Toxicology, and Bioanalytical Research organization at Lilly is seeking an experienced scientist to lead the Bioanalytical Research (BAR) team located at our Louisville, CO facility. The research focus of this team is developing and employing mass spectrometric applications to investigate the ADME properties of radio-ligand therapeutics (RLTs), Antibody-Drug Conjugates (ADCs), and small molecule xenobiotics to discover and characterize optimal drug candidates to progress to clinical development.

Key Responsibilities

Building and leading an innovative bioanalytical research team, with associated analytical strategies, to deliver pharmacokinetic (PK), biotransformation (BioT), and biodistribution (BioD) data to program teams developing RLTs, ADCs, or small molecule drugs.The supervision and career development of junior laboratory scientists and scientific contractors.The management, prioritization, and delivery of bioanalytical support to a large and diverse spectrum of drug program teams.The technical development and implementation of mass spectrometric approaches (QQQ, high-resolution, and ICP-MS) to investigate the PK, BioT, and BioD of novel drug candidates in pre-clinical animal models.Serving as the bioanalytical lead on discovery programs, partnering closely with cross‑functional teams including ADME, Toxicology, Chemistry, therapeutic areas (Oncology, e.g.), and Biotechnology Discovery Research.Interpreting innovative MS datasets and presenting clear, actionable scientific insights to program teams and ADME Project Leaders.

Required Qualifications

MS in one of these fields' chemistry, biochemistry, engineering, pharmacology, or an associated field with 10+ years of industry experience wHands‑on experience in the application of LC-MS for the bioanalysis of ADCs or small molecule drugs. This includes experience with advanced sample preparation techniques such as LLE, SPE, microwave digestion, and/or immunoaffinity capture approaches.Excellent scientific communication, problem‑solving, and project‑level collaboration skills.

Preferred Qualifications

A PhD in chemistry, biochemistry, engineering, pharmacology, or an associated field with 3+ years of relevant experienceExperience supervising laboratory staff.Expertise with MS‑informatics tools such as Proteome Discoverer, Protein Metrics, DAR workflows, MassMetaSite, and Biopharma Finder.Knowledge of drug ADME principles.Hands-on experience developing and implementing ICP-MS assays to study RLTs or imaging agents.Experience developing and implementing automation for in vivo or high-throughput in vitro metabolism screens is highly desirable (Tecan, Hamilton, KingFisher, e.g.).

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$166,500 - $266,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly